The recommended starting dose of Korlym is 300 mg per day1

Korlym® (mifepristone) 300 mg tablet.

300 mg

  • The dose of Korlym may be increased in 300-mg increments to a maximum of 1200 mg/day1

  • Increases in dose should not occur more frequently than once every 2-4 weeks1

  • For patients with renal impairment or mild-to-moderate hepatic impairment, no change in initial Korlym dose is required. The maximum dose should be limited to 600 mg/day1

  • Most patients (85%) achieved an initial positive response by titrating up from 300 mg/day2

  1. Korlym Prescribing Information. Corcept Therapeutics, Inc; 2019.
  2. Yuen KCJ, Williams G, Kushner H, Nguyen D. Association between mifepristone dose, efficacy, and tolerability in patients with Cushing syndrome. Endocr Pract. 2015;21(10):1087-1092. doi:10.4158/EP15760.OR