Clinical trial results

How Korlym® may help

Korlym is a once-daily oral treatment that helps reduce the negative effects of excess cortisol activity.

Korlym was studied in a clinical trial* of 50 adults with endogenous Cushing syndrome who had type 2 diabetes mellitus or glucose intolerance and who could not have surgery or for whom surgery had failed.

Some improvements may happen quickly and can be assessed by your healthcare provider within 6 weeks of treatment. In the Korlym clinical trial:

An icon of a glucose monitor touching someone's finger

3 out of 5 people saw improvements in their blood sugars

An icon of a pill bottle

1 out of 2 people had less need for antidiabetic medicine

An icon of a sun to represent improvements in mood and memory

1 out of 2 people experienced improvements in their mood and focus

Other improvements may happen over time and can be assessed by your healthcare provider 2 months into treatment. You may see improvements in:

  • Round and reddened face (moon face)

  • Acne

  • Unwanted hair growth or hair loss

  • Stretch marks

  • Weight loss

Results are from an open-label study of Korlym. Assessment was based on 8 broad categories: glucose control, lipids, blood pressure, body composition, clinical appearance, strength, psychiatric symptoms, and quality of life.

It is uncertain whether changes were the result of the effects of Korlym. Participants in the clinical trial reported various symptoms and results throughout the study.

Starting treatment with Korlym
Learn what to know before starting Korlym and what you can expect during treatment.

Learn more about treatment with Korlym