Possible side effects

What you might experience during treatment

Your body may have become used to excess cortisol. When Korlym® begins to compete with cortisol activity, you may experience symptoms of cortisol withdrawal. Cortisol withdrawal can cause flu-like symptoms. Some of these symptoms include tiredness, headaches, nausea, and joint pain. Inform your healthcare provider immediately if you experience symptoms of cortisol withdrawal.

Additional common side effects include:

  • Vomiting

  • Decreased appetite

  • Arm pain (arthralgia)

  • Arm and leg swelling (peripheral edema)

  • Dizziness

  • High blood pressure (hypertension)

  • Low potassium in your blood (hypokalemia)

  • Thickening of the uterine lining (endometrial hypertrophy)

Avoid grapefruit juice, as it may increase the chance of side effects.

Korlym may also cause:

  • Problems with your adrenal glands

  • Muscle aches and cramps or irregular heartbeat (palpitations), which could all be a sign of low potassium levels

  • Unusual vaginal bleeding or changes in your menstrual cycle

  • Changes in your blood sugar or blood pressure

Starting treatment with Korlym
Learn what to know before starting Korlym and what you can expect during treatment.

Learn more about treatment with Korlym